Which statement about detection of protein tumor markers is false?

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Multiple Choice

Which statement about detection of protein tumor markers is false?

Explanation:
Detecting protein tumor markers relies on recognizing specific proteins with antibodies. Electrophoresis can separate proteins to reveal abnormal patterns or levels, ELISA uses antibodies to quantify a particular protein, and agglutination assays detect a protein antigen by visible clumping of particles. The hybrid capture approach, however, is a nucleic acid–based method that detects target DNA or RNA through hybridization and capture, not a protein. Because it targets nucleic acids rather than proteins, it isn’t appropriate for detecting protein tumor markers. That’s why the statement describing hybrid capture for protein detection is false.

Detecting protein tumor markers relies on recognizing specific proteins with antibodies. Electrophoresis can separate proteins to reveal abnormal patterns or levels, ELISA uses antibodies to quantify a particular protein, and agglutination assays detect a protein antigen by visible clumping of particles. The hybrid capture approach, however, is a nucleic acid–based method that detects target DNA or RNA through hybridization and capture, not a protein. Because it targets nucleic acids rather than proteins, it isn’t appropriate for detecting protein tumor markers. That’s why the statement describing hybrid capture for protein detection is false.

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