Which marker is NOT part of the IHC panel for primary mixed thyroid tumor?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Prepare for the CMID Test. Study with flashcards and multiple choice questions, each question contains hints and explanations. Get ready for your exam with confidence!

Multiple Choice

Which marker is NOT part of the IHC panel for primary mixed thyroid tumor?

Explanation:
In a primary mixed thyroid tumor, the IHC panel is aimed at capturing both cell lineages present: thyroid follicular epithelium and neuroendocrine differentiation. Markers like TTF-1 and thyroglobulin confirm thyroid epithelial origin, while chromogranin highlights a neuroendocrine component such as medullary-like tissue. Cytokeratin 19 can be expressed in papillary thyroid carcinoma, but it is not specific or essential for identifying a mixed tumor’s two components, and its expression is variable across cases. Because it doesn’t add decisive information about the dual nature of the tumor, Cytokeratin 19 is not typically included in this panel.

In a primary mixed thyroid tumor, the IHC panel is aimed at capturing both cell lineages present: thyroid follicular epithelium and neuroendocrine differentiation. Markers like TTF-1 and thyroglobulin confirm thyroid epithelial origin, while chromogranin highlights a neuroendocrine component such as medullary-like tissue. Cytokeratin 19 can be expressed in papillary thyroid carcinoma, but it is not specific or essential for identifying a mixed tumor’s two components, and its expression is variable across cases. Because it doesn’t add decisive information about the dual nature of the tumor, Cytokeratin 19 is not typically included in this panel.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy