Which designation is used for noninvasive, at-origin disease?

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Multiple Choice

Which designation is used for noninvasive, at-origin disease?

Explanation:
Noninvasive, at-origin disease is labeled as Tis. In the TNM system, Tis means carcinoma in situ—cancer cells are present at the original site but have not invaded through the basement membrane into surrounding tissues. It is confined to where it started and has not spread locally. By contrast, T0 means there is no evidence of a primary tumor, while T1 through T4 describe increasing depths of invasion, and Tx means the primary tumor cannot be assessed. So Tis best captures the idea of cancer that is at its origin without invasion.

Noninvasive, at-origin disease is labeled as Tis. In the TNM system, Tis means carcinoma in situ—cancer cells are present at the original site but have not invaded through the basement membrane into surrounding tissues. It is confined to where it started and has not spread locally. By contrast, T0 means there is no evidence of a primary tumor, while T1 through T4 describe increasing depths of invasion, and Tx means the primary tumor cannot be assessed. So Tis best captures the idea of cancer that is at its origin without invasion.

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