Which breast cancer grouping corresponds to estrogen receptor positive and HER2 positive status?

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Multiple Choice

Which breast cancer grouping corresponds to estrogen receptor positive and HER2 positive status?

Explanation:
Breast cancer subtypes are defined by hormone receptor status and HER2 status. When a tumor is estrogen receptor positive and also HER2 positive, it fits the luminal B category. This means the cancer relies on estrogen signaling but also shows HER2 amplification, making it more proliferative than luminal A and requiring consideration of both endocrine therapy and HER2-targeted therapy. Luminal A is typically ER+/PR+ with HER2 negative and lower proliferation, HER2-enriched is ER-/PR-/HER2+, and triple negative lacks all three receptors. So the ER-positive and HER2-positive combination corresponds to luminal B.

Breast cancer subtypes are defined by hormone receptor status and HER2 status. When a tumor is estrogen receptor positive and also HER2 positive, it fits the luminal B category. This means the cancer relies on estrogen signaling but also shows HER2 amplification, making it more proliferative than luminal A and requiring consideration of both endocrine therapy and HER2-targeted therapy. Luminal A is typically ER+/PR+ with HER2 negative and lower proliferation, HER2-enriched is ER-/PR-/HER2+, and triple negative lacks all three receptors. So the ER-positive and HER2-positive combination corresponds to luminal B.

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