Which biomarker is not mentioned as part of the endometrial cancer profiling panels?

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Multiple Choice

Which biomarker is not mentioned as part of the endometrial cancer profiling panels?

Explanation:
Endometrial cancer profiling panels focus on markers that help classify tumor biology and guide treatment. p53 status helps identify TP53-mutant, serous-like tumors with poorer prognosis; p16 is used as a surrogate marker for certain pathways and supports tumor characterization; ER status informs potential responsiveness to hormonal therapies. HER2 testing is not typically part of standard endometrial cancer profiling panels, though it can be assessed in some serous cases to consider targeted therapy. Therefore, the biomarker not usually included is HER2.

Endometrial cancer profiling panels focus on markers that help classify tumor biology and guide treatment. p53 status helps identify TP53-mutant, serous-like tumors with poorer prognosis; p16 is used as a surrogate marker for certain pathways and supports tumor characterization; ER status informs potential responsiveness to hormonal therapies. HER2 testing is not typically part of standard endometrial cancer profiling panels, though it can be assessed in some serous cases to consider targeted therapy. Therefore, the biomarker not usually included is HER2.

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