What was the first FNA-cleared digital cytology system?

• A. Cytomatrix
• B. Leica Cytom
• C. Philips Aurora
• D. Hologic Genius

Answer: (D)

The key idea is regulatory approval for using digital slides to diagnose fine-needle aspiration (FNA) samples. In cytology, FNA yields small cell clusters that doctors evaluate under the microscope, so a digital system must prove it can match traditional microscopy for that specific use before being cleared for primary diagnosis. Hologic Genius was the first to receive FDA clearance for digital cytology with FNA, establishing a path for digital review of these specimens and enabling telecytology workflows. Other scanners and platforms exist, but they either entered the market later or were cleared for different indications, not the first FNA-specific clearance.