What treatment option is available for someone with a HER2 mutation?

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Multiple Choice

What treatment option is available for someone with a HER2 mutation?

Explanation:
HER2 drives cancer growth when it’s overexpressed or mutated, so blocking that receptor directly can stop the cancer’s growth signals. Trastuzumab (Herceptin) is a monoclonal antibody that binds to HER2, inhibiting the signaling and helping the immune system attack the cancer cells. That targeted approach addresses the specific abnormal driver in HER2-positive cancers, making it the best option here. Gefitinib and Erlotinib target EGFR (HER1), not HER2, so they don’t address HER2-driven tumors. Tamoxifen blocks estrogen receptor signaling and is used for hormone receptor–positive breast cancers, not for HER2-driven cases.

HER2 drives cancer growth when it’s overexpressed or mutated, so blocking that receptor directly can stop the cancer’s growth signals. Trastuzumab (Herceptin) is a monoclonal antibody that binds to HER2, inhibiting the signaling and helping the immune system attack the cancer cells. That targeted approach addresses the specific abnormal driver in HER2-positive cancers, making it the best option here.

Gefitinib and Erlotinib target EGFR (HER1), not HER2, so they don’t address HER2-driven tumors. Tamoxifen blocks estrogen receptor signaling and is used for hormone receptor–positive breast cancers, not for HER2-driven cases.

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