Pembrolizumab is a monoclonal antibody targeting which molecule?

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Multiple Choice

Pembrolizumab is a monoclonal antibody targeting which molecule?

Explanation:
Pembrolizumab targets PD-1, a receptor on activated T cells. When PD-1 binds its ligands PD-L1 or PD-L2, T-cell activity is inhibited. By binding PD-1, pembrolizumab blocks this interaction, releasing the brake on T cells and allowing them to mount a stronger attack against tumor cells. This differs from antibodies that target PD-L1 itself, CTLA-4, or VEGF, which affect different molecules or pathways.

Pembrolizumab targets PD-1, a receptor on activated T cells. When PD-1 binds its ligands PD-L1 or PD-L2, T-cell activity is inhibited. By binding PD-1, pembrolizumab blocks this interaction, releasing the brake on T cells and allowing them to mount a stronger attack against tumor cells. This differs from antibodies that target PD-L1 itself, CTLA-4, or VEGF, which affect different molecules or pathways.

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