Is PSMA positive in both benign prostatic hyperplasia (BPH) and prostatic adenocarcinoma?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Prepare for the CMID Test. Study with flashcards and multiple choice questions, each question contains hints and explanations. Get ready for your exam with confidence!

Multiple Choice

Is PSMA positive in both benign prostatic hyperplasia (BPH) and prostatic adenocarcinoma?

Explanation:
PSMA expression isn't exclusive to cancer. The PSMA protein is present in normal prostate tissue and in benign conditions like BPH, as well as being overexpressed in many prostate cancers. So PSMA-based imaging can show uptake in both BPH and prostatic adenocarcinoma. The key point is that cancer usually shows higher, more focal uptake, while BPH tends to have lower or more diffuse uptake. In practice, interpretation combines uptake patterns with MRI, biopsy results, and clinical context to distinguish benign from malignant tissue.

PSMA expression isn't exclusive to cancer. The PSMA protein is present in normal prostate tissue and in benign conditions like BPH, as well as being overexpressed in many prostate cancers. So PSMA-based imaging can show uptake in both BPH and prostatic adenocarcinoma. The key point is that cancer usually shows higher, more focal uptake, while BPH tends to have lower or more diffuse uptake. In practice, interpretation combines uptake patterns with MRI, biopsy results, and clinical context to distinguish benign from malignant tissue.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy