CA125 is specific for ovarian cancers. True or False?

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Multiple Choice

CA125 is specific for ovarian cancers. True or False?

Explanation:
CA125 is a marker that can be elevated in ovarian cancer, but it is not unique to it. Levels can rise in many benign gynecologic conditions (like endometriosis and fibroids), other inflammatory or liver diseases, pregnancy, and in a variety of non-gynecologic cancers. Because of this lack of specificity, a high CA125 value by itself cannot confirm ovarian cancer. It’s most useful when combined with imaging and clinical evaluation, especially for monitoring response to treatment or detecting recurrence in someone with a known ovarian cancer. So, the statement that CA125 is specific for ovarian cancers is false.

CA125 is a marker that can be elevated in ovarian cancer, but it is not unique to it. Levels can rise in many benign gynecologic conditions (like endometriosis and fibroids), other inflammatory or liver diseases, pregnancy, and in a variety of non-gynecologic cancers. Because of this lack of specificity, a high CA125 value by itself cannot confirm ovarian cancer. It’s most useful when combined with imaging and clinical evaluation, especially for monitoring response to treatment or detecting recurrence in someone with a known ovarian cancer. So, the statement that CA125 is specific for ovarian cancers is false.

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